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Czystek – cudowny lek czy zwykła ściema?

Czystek – cudowny lek czy zwykła ściema?


Czystek – kolejna z roślin polecana na praktycznie wszystko – od boreliozy po oczyszczanie organizmu z metali ciężkich przez cuchnące stopy (tutaj akurat wystarczy higiena i dobry antyperspirant, ale co ja mogę wiedzieć 😛 ). Zmysł naukowca jak zwykle w takich wypadkach zawył ostrzegawczo – im więcej działań się przypisuje, tym większe ryzyko, że okaże się to ściemą. Sami pamiętacie jak było w przypadku żyworódki – cudowna roślinka okazała się niebezpieczna, szczególnie przy dłuższym stosowaniu.

Jakie substancje biologicznie czynne zawiera czystek?

Nasza roślina zawiera flawonoidy, głównie pochodne flawanolowe takie, jak mirycetyna, kwercetyna, czy kemferol. Obecne są również elagotaniny, między innymi punikalina i punikalagina.
Do tego dochodzi nam olejek eteryczny, zawierający fitosterole i diterpeny labdanowe.

Na co możemy stosować czystek?

Przeciwko boreliozie?

Jeśli chodzi o najbardziej kontrowersyjną według mnie aktywność – przeciwko boreliozie – jak dotąd znalazłem jedno badanie. Według niego olejek eteryczny pozyskany z czystka był skuteczny przeciwko bakterii Borrelia burgdorferi sensu stricto. Ale po pierwsze to były badania in vitro – hodowla bakterii na specjalnych płytkach pokrytych agarem – nie wiadomo, czy pijąc herbatkę z czystka możemy otrzymać takie same stężenie w naszym organizmie, jak bezpośrednio zakrapiając bakterie olejkiem. Po drugie nie zbadano czystka jako takiego – zbadano jego olejek, którego w roślinie jest zwykle góra kilka procent. Dlatego zdecydowanie odradzam stosowanie samego czystka w terapii boreliozy. Jako wspomaganie przy terapii antybiotykami jak najbardziej. W takim wypadku może działać korzystnie, ale sam czystek w tak poważnej chorobie, może nam zapewnić jedynie ciężkie powikłania.

W terapii stanów zapalnych?

Wykazano również, że działa przeciwzapalnie przez hamowanie cyklooksygenazy (pamiętacie reklamę, w której chwalili się, że jeden ze środków zawiera inhibitor COX? W sumie to 90% preparatów przeciwbólowych i przeciwzapalnych zawiera związki, które są „inhibitorami COX”. Ale do sedna – czystek też tak działa).

W infekcjach wirusowych?

Wykazano również, że działa przeciwwirusowo, prawdopodobnie przez wiązanie się z otoczką wirusów i uniemożliwienie im wnikania do komórek. W porównaniu z grupą kontrolną wykazano znaczną poprawę stanu pacjentów, szczególnie tych zakażonych wirusem grypy. Przy takim mechanizmie działania jest skuteczniejszy w zapobieganiu infekcjom wirusowym, ale w leczeniu już trwającej choroby też powinien pomóc. Udało się również stwierdzić skuteczność przeciwko wirusom HIV-1 i HIV-2, ale w tym przypadku poczekałbym na solidne badanie na ludziach.

W problemach z odpornością?

Spotkałem się kilkukrotnie ze stwierdzeniem, że czystek poprawia naszą odporność, co uważam za zwyczajną ściemę. Jak mówią badania czystek wręcz hamuje aktywność naszych białych krwinek, co może w pewien sposób być porównane do działania leków sterydowych takich jak hydrokortyzon.

We wrzodach żołądka?

Jeśli pijecie czystek, żeby podleczyć swoje wrzody żołądka – robicie to słusznie. Co prawda musimy zadowolić się badaniami na szczurach, ale wyniki są bardzo obiecujące – ekstrakty z czystka wykazały się w zmniejszaniu objawów uszkodzeń śluzówki żołądka wywołanych różnymi substancjami, najskuteczniej w przypadku tych spowodowanych przez rezerpinę i serotoninę.

W infekcjach bakteryjnych

Może zastanawiacie się, czy czystek działa przeciwbakteryjnie? Działa i jak się okazuje dodatkowo zmniejsza tworzenie się tzw. biofilmu bakteryjnego (gęsty glut, w którym bakterie mają dobre warunki do życia, przez który słabo przenikają antybiotyki i nasze komórki odpornościowe). Penicylina to nie jest, ale dzięki jego właściwościom możemy wykorzystać herbatkę z czystka jako całkiem niezłą płukankę do jamy ustnej.

W przeroście prostaty?

Ostatnie badania, które dzisiaj zacytuję wykazały, że może również być skuteczny w terapii nieznacznego przerostu prostaty.

Podsumowanie:

Jak widać, czystek przynajmniej w pewnym stopniu zasłużył sobie na swoją sławę. Może nie mamy solidnych dowodów na to, że leczy boreliozę, HIV i śmierdzące stopy, ale jako terapia wspomagająca (przynajmniej w dwóch z trzech wymienionych przeze mnie przypadków) może przynieść nam rzeczywiste korzyści. Warto popijać go, żeby zabezpieczyć się przed infekcjami wirusowymi czy bakteryjnymi, może pomóc nam w leczeniu wrzodów żołądka i służyć za ciekawą płukankę do ust.

A jak wygląda bezpieczeństwo? Czy czystek można pić nie obawiając się działań niepożądanych?

Otóż można. Jak wykazało jedno z badań na ludziach – 17% pacjentów przyjmujących wyciągi z czystka zgłaszało różne objawy uboczne, z kolei tzw. w grupie placebo (przyjmującej jakąś obojętną substancję zamiast naszych ekstraktów) objawy niepożądane zgłaszało 20% pacjentów. Ciekawe, nieprawdaż?

Źródła:

  • Hutschenreuther A, Birkemeyer C, Grötzinger K, Straubinger RK, Rauwald HW. Growth inhibiting activity of volatile oil from Cistus creticus L. against Borrelia burgdorferi s.s. in vitro. Pharmazie. 2010 Apr;65(4):290-5.
  • Mansoor KA, Matalka KZ, Qa’dan FS, Awad R, Schmidt M. Two new proanthocyanidin trimers isolated from Cistus incanus L. demonstrate potent anti-inflammatory activity and selectivity to cyclooxygenase isoenzymes inhibition. Nat Prod Res. 2016 Sep;30(17):1919-26. doi: 10.1080/14786419.2015.1089242.
  • Lendeckel U, Arndt M, Wolke C, Reinhold D, Kähne T, Ansorge S. Inhibition of human leukocyte function, alanyl aminopeptidase (APN, CD13) and dipeptidylpeptidase IV (DP IV, CD26) enzymatic activities by aqueous extracts of Cistus incanus L. ssp. incanus. J Ethnopharmacol. 2002 Feb;79(2):221-7.
  • Droebner K, Ehrhardt C, Poetter A, Ludwig S, Planz O. CYSTUS052, a polyphenol-rich plant extract, exerts anti-influenza virus activity in mice. Antiviral Res. 2007 Oct;76(1):1-10. Epub 2007 May 15.
  • Kalus U, Grigorov A, Kadecki O, Jansen JP, Kiesewetter H, Radtke H. Cistus incanus (CYSTUS052) for treating patients with infection of the upper respiratory tract. A prospective, randomised, placebo-controlled clinical study. Antiviral Res. 2009 Dec;84(3):267-71. doi: 10.1016/j.antiviral.2009.10.001. Epub 2009 Oct 12 pl.wikipedia.org.
  • Mansoor KA, Matalka KZ, Qa’dan FS, Awad R, Schmidt M. Two new proanthocyanidin trimers isolated from Cistus incanus L. demonstrate potent anti-inflammatory activity and selectivity to cyclooxygenase isoenzymes inhibition. Nat Prod Res. 2016 Sep;30(17):1919-26. doi: 10.1080/14786419.2015.1089242. Epub 2015 Sep 28.
  • Stephanie Rebensburg, Markus Helfer, Martha Schneider, Herwig Koppensteiner, Josef Eberle, Michael Schindler, Lutz Gürtler, and Ruth Brack-Wernera. Potent in vitro antiviral activity of Cistus incanus extract against HIV and Filoviruses targets viral envelope proteins. Sci Rep. 2016; 6: 20394. doi:  10.1038/srep20394
  • Attaguile G, Caruso A, Pennisi G, Savoca F. Gastroprotective effect of aqueous extract of Cistus incanus L. in rats. Pharmacol Res. 1995 Jan;31(1):29-32.
  • Wittpahl G, Kölling-Speer I, Basche S, Herrmann E, Hannig M, Speer K, Hannig C. The Polyphenolic Composition of Cistus incanus Herbal Tea and Its Antibacterial and Anti-adherent Activity against Streptococcus mutans. Planta Med. 2015 Dec;81(18):1727-35. doi: 10.1055/s-0035-1557822.

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